Solvent-free multicomponent synthesis of 2-arylpyridines using p-sulfonic acid calix[6]arene as a reusable catalyst
dc.contributor.author | Liberto, Natália Aparecido | |
dc.contributor.author | Fernandes, Sérgio Antônio | |
dc.contributor.author | Romanelli, Gustavo Pablo | |
dc.contributor.author | Sathicq, Ángel G. | |
dc.date.accessioned | 2018-11-28T13:35:37Z | |
dc.date.available | 2018-11-28T13:35:37Z | |
dc.date.issued | 2015-04 | |
dc.description.abstract | An efficient methodology for obtaining 2-arylpyrimidines based on the use of p-sulfonic acid calix[6]arene as an organocatalyst is proposed. The methodology involves the formation of 1,2-dihydropyridine intermediates using a variety of aromatic aldehydes with methyl or ethyl acetoacetate and ammonium acetate, which are the same starting materials as in the Hantzsch reaction, under solvent-free reaction conditions, at 25 °C, followed by air oxidation for 12 h. The catalyst efficiency is not compromised after its successive use in reactions. Eleven examples were obtained with very good to excellent yields of 2-arylpyridines (92–62%). This is the first report about the use of calixarenes as catalysts in the multicomponent synthesis of 2-arylpyridines (molecules with potential biological activity). | en |
dc.format | pt-BR | |
dc.identifier.issn | 1631-0748 | |
dc.identifier.uri | https://doi.org/10.1016/j.crci.2014.08.006 | |
dc.identifier.uri | http://www.locus.ufv.br/handle/123456789/22615 | |
dc.language.iso | eng | pt-BR |
dc.publisher | Comptes Rendus Chimie | pt-BR |
dc.relation.ispartofseries | Volume 18, Issue 4, Pages 374-378, April 2015 | pt-BR |
dc.rights | 2014 Académie des sciences. Published by Elsevier Masson SAS. All rights reserved. | pt-BR |
dc.subject | 2-Arylpyridines | pt-BR |
dc.subject | P-Sulfonic acid calix[6]arene | pt-BR |
dc.subject | Organocatalyts | pt-BR |
dc.subject | Solvent-free conditions | pt-BR |
dc.subject | Oxidant-free conditions | pt-BR |
dc.title | Solvent-free multicomponent synthesis of 2-arylpyridines using p-sulfonic acid calix[6]arene as a reusable catalyst | en |
dc.type | Artigo | pt-BR |
Arquivos
Pacote original
1 - 1 de 1
Nenhuma Miniatura Disponível
- Nome:
- artigo.pdf
- Tamanho:
- 541.68 KB
- Formato:
- Adobe Portable Document Format
- Descrição:
- Texto completo
Licença do pacote
1 - 1 de 1
Nenhuma Miniatura Disponível
- Nome:
- license.txt
- Tamanho:
- 1.71 KB
- Formato:
- Item-specific license agreed upon to submission
- Descrição: