Ferreira, Silvio C.Santalla, Silvia N.2019-04-112019-04-112018-0805562813https://doi.org/10.1103/PhysRevE.98.022405http://www.locus.ufv.br/handle/123456789/24495We investigate an off-lattice Eden model where the growth of new cells is performed with a probability dependent on the availability of resources coming externally towards the growing aggregate. The concentration of nutrients necessary for replication is assumed to be proportional to the voids connecting the replicating cells to the outer region, introducing therefore a nonlocal dependence on the replication rule. Our simulations point out that the Kadar–Parisi–Zhang (KPZ) universality class is a transient that can last for long periods in plentiful environments. For conditions of nutrient scarcity, we observe a crossover from regular KPZ to unstable growth, passing by a transient consistent with the quenched KPZ class at the pinning transition. Our analysis sheds light on results reporting on the universality class of kinetic roughening in akin experiments of biological growth.pdfengOpen AcessEden modelBiological systemsArtigo