Demuner, Antônio J.Barbosa, Luiz C. A.Veiga, Thiago A. M.Barreto, Robert W.King-Diaz, BeatrizLotina-Hennsen, Blas2018-10-192018-10-192006-1103051978https://doi.org/10.1016/j.bse.2006.06.008http://www.locus.ufv.br/handle/123456789/22344A phytotoxic compound identified as 6-(3,3-dimethylallyloxy)-4-methoxy-5-methylphthalide (1), was isolated from the phytopathogenic fungus Nimbya alternantherae, cultivated on solid media. Catalytic hydrogenation of 1 resulted in the quantitative formation of second compound (2). Both compounds (1, 2) act by inhibiting the ATP synthesis in spinach thylakoids. A detailed investigation on the mechanism of action indicates that compound 1 acts as a Hill reaction inhibitor and uncoupler of photosynthesis.pdfengElsevier Ltd.Natural herbicideAnamorphic fungiWeedAlligator weedBiological controlLactonePhotosynthesis inhibitorArtigo