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URI permanente para esta coleçãohttps://locus.ufv.br/handle/123456789/11851
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Item Increased ApoB/ApoA1 ratio is associated with excess weight, body adiposity, and altered lipid profile in children(Jornal de Pediatria, 2018-02-10) Castro, Ana Paula Pereira; Hermsdorff, Helen Hermana Miranda; Milagres, Luana Cupertino; Albuquerque, Fernanda Martins; Filgueiras, Mariana de Santis; Rocha, Naruna Pereira; Novaes, Juliana Farias deTo investigate ApoB/ApoA1 ratio and its association with cardiovascular risk factors in children. Cross-sectional study with 258 children aged 8 and 9 years old, enrolled in all urban schools in the city of Viçosa-MG. Anthropometric and body composition assessment, as well as biochemical profile of the children was performed. Socioeconomic variables and sedentary lifestyle were evaluated through a semi-structured questionnaire. Many children had excess weight (35.2%), abdominal adiposity (10.5%), and body fat (15.6%), as well as increased ApoB/ApoA1 ratio (14.7%), total cholesterol (51.8%), and triglycerides (19.8%). Children with excess weight and total and central fat had a higher prevalence of having a higher ApoB/ApoA1 ratio, as well as those with atherogenic lipid profile (increased LDL-c and triglycerides and low HDL-c). A direct association was found between the number of cardiovascular risk factors and the ApoB/ApoA1 ratio (p = 0.001), regardless of age and income. The increased ApoB/ApoA1 ratio was associated with excess weight, body adiposity (total and central), and altered lipid profile in children. Children with a higher number of cardiovascular risk factors had higher ApoB/ApoA1 ratio, in both genders.