Navegando por Autor "Silva, Marco Túlio C."

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    Fatty acid composition of mature breast milk in Brazilian women
    (Food Chemistry, 2005-11) Silva, Maurício H.L.; Silva, Marco Túlio C.; Brandão, Sebastião C.C.; Gomes, José C.; Peternelli, Luiz A.; Franceschini, Sylvia do C.C.
    This work analyzed the fatty acid composition of mature milk samples, weekly obtained from eight Brazilian women between the 4th and 13th lactation weeks. A questionnaire was weekly applied to observe their eating habits. Saturated fatty acids constituted 39.7% of the total fatty acids. De novo fatty acids and long chain saturated fatty acids presented levels of 15.9% and 23.8%, respectively. trans-Fatty acid content was very low (2.36%). Unsaturated fatty acids constituted 50.9% of the total fatty acids, with over half being monounsaturated fatty acids (27.6%). Polyunsaturated fatty acids showed levels of 23.3%, with high linoleic and α-linolenic acid contents (20.3% and 1.43%, respectively). Arachidonic acid had a content of 0.53%, while docosahexaenoic acid content was 0.14%, values considered adequate for the needs of breast-fed infants.
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    Lipid profile of rats fed high-fat diets based on flaxseed, peanut, trout, or chicken skin
    (Nutrition, 2005-09-03) Cintra, Dennys E. C.; Costa, André G. V.; Peluzio, Maria do Carmo G.; Matta, Sérgio L. P.; Silva, Marco Túlio C.; Costa, Neuza M. B.
    Dietary saturated fatty acids are associated with coronary disease. Conversely, dietary monounsaturated polyunsaturated fatty acids (MUFAs) and polyunsaturated fatty acids (PUFAs) seem to exert a protective effect. This study evaluated the lipid profile of rats fed high-fat (HF) diets, with fat added as different sources of PUFA (flaxseed and trout), MUFA (peanut), and saturated fatty acid (chicken skin). Adult male Wistar rats were placed into six dietary groups (n = 10): control (normal); high fat, with 1% cholesterol, 10% soy oil, and 5% lard; and four groups fed similar HF diets, with 10% lipid as trout, flaxseed, peanut, or chicken skin. After 28 d the animals were killed. Blood, livers, and adipose tissue samples were collected. A higher level (P < 0.05) of total serum cholesterol was observed in rats fed the normal diet (93.57 ± 14.95 mg/dL) compared with those fed the HF diet (67.57 ± 12.54 mg/dL). Total cholesterol levels in rats fed the flaxseed diet were lower (P < 0.05) than in rats fed the other fats. No difference was observed in cholesterol levels between groups fed the peanut and chicken skin diets (P > 0.05). Animals fed the peanut diet showed decreased body weight gain than did animals in the other treatment groups. There were large lipid and cholesterol depositions in livers of rats fed the HF diet. Lipid deposition in adipose tissue followed the same dietary fatty acid profile, i.e., high levels of ω-3 PUFA in the flaxseed group, high levels of MUFA in the peanut and chicken skin groups and high levels of ω-6 PUFA in the trout group. These data indicate that flaxseed is promising for dietary manipulation of hyperlipidemia.