Navegando por Autor "Cerqueira, Fábio Ribeiro"

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    CD4+CD25+ T lymphocytes and regulation of the immune system: perspectives for a pathophysiological understanding of sepsis
    (Revista Brasileira de Terapia Intensiva, 2012-09-28) Batista, Rodrigo Siqueira; Gomes, Andréia Patrícia; Azevedo, Sarah Fumian Milward; Vitorino, Rodrigo Roger; Mendonça, Eduardo Gomes de; Sousa, Flávio Oliveira de; Oliveira, Alcione de Paiva; Cerqueira, Fábio Ribeiro; Paula, Sérgio Oliveira de; Oliveira, Maria Goreti de Almeida
    The systemic inflammatory response represents the core pathogenic event of sepsis, underlying clinical manifestations and laboratory findings in patients. Numerous studies have shown that CD4+CD25+ T lymphocytes, also known as regulatory T lymphocytes (Treg), participate in the development of sepsis due to their ability to suppress the immune response. The present article discusses the role of Treg lymphocytes in sepsis based on a specific search strategy (Latin American and Caribbean Health Sciences / Literatura Latino-americana e do Caribe em Ciências da Saúde - LILACS, PubMed, and Scientific Electronic Library Online - SciELO) focusing on two main topics: the participation of Treg cells in inflammation and immunity as well as perspectives in the computational physiological investigation of sepsis.