Use este identificador para citar ou linkar para este item: https://locus.ufv.br//handle/123456789/16063
Tipo: Artigo
Título: High-oleic peanuts: New perspective to attenuate glucose homeostasis disruption and inflammation related obesity
Autor(es): Alves, Raquel Duarte Moreira
Moreira, Ana Paula Boroni
Macedo, Viviane Silva
Bressan, Josefina
Alfenas, Rita de Cássia Gonçalves
Mattes, Richard
Costa, Neuza Maria Brunoro
Abstract: To evaluate the effects of acute and daily consumption of high-oleic peanuts (HOP) on inflammation and glucose homeostasis in overweight/obese men. In a 4-week randomized clinical trial, males with body mass index of 29.8 ± 2.3 kg/m(2) and aged 18-50 years were assigned to the groups: control (CT, n = 22); conventional peanuts (CVP, n = 22); or HOP (n = 21). They followed a hypocaloric-diet with or without 56 g/day of CVP or HOP. Main outcomes were changes in fasting blood biomarkers and postprandial insulin, glucose, tumor necrosis factor-alfa (TNF-α), and interleukin-10 (IL-10) responses after acute peanut intake. At baseline, HOP showed significantly lower postprandial responses of glucose, insulin, and TNF-α than CVP and CT. Changes in fasting blood biomarkers did not differ between groups after the 4-week intervention. However, within groups, total cholesterol decreased in CT, and all groups reduced High-density lipoprotein (HDL-c). Triglycerides were reduced in HOP and CVP. IL-10 increased significantly in all groups while only the CT and CVP showed increased TNF-α after intervention. Acute high-oleic peanut consumption leads to stronger moderation of postprandial glucose, insulin, and TNF-α concentrations than CVP and control meal intake. Whether daily intake of high-oleic peanuts has additional benefits to CVP remains uncertain.
Palavras-chave: Peanuts
Glucose homeostasis
Obesity
Editor: The Obesity Society
Tipo de Acesso: Open Access
URI: http://dx.doi.org/doi:10.1002/oby.20825
http://www.locus.ufv.br/handle/123456789/16063
Data do documento: 27-Jun-2014
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