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https://locus.ufv.br//handle/123456789/17583
Tipo: | Artigo |
Título: | A reação "click" na síntese de 1,2,3-triazóis: aspectos químicos e aplicações |
Autor(es): | Freitas, Luiza Baptista de Oliveira Ruela, Fernando Armini Pereira, Guilherme Rocha Alves, Rosemeire Brondi Freitas, Rossimiriam Pereira de Santos, Leandro José dos |
Abstract: | The Copper-catalyzed azide-alkyne cycloaddition (CuAAC), often referred to as "click" reaction, has become a very popular reaction in the last years. It affords exclusively 1,4-disubstituted 1,2,3-triazoles and has been widely used to connect readily accessible building blocks containing various functional groups. The great success of this reaction is based on the fact that it is general, virtually quantitative and very robuste. The scope of this copper-catalyzed synthesis is extraordinary and the reaction has found numerous applications in many research fields, including biological chemistry and materials science. In this review, the main chemical aspects and applications of the "click" reaction in the synthesis of 1,2,3-triazoles are presented. |
Palavras-chave: | "Click" reaction Cycloaddition Triazole |
Editor: | Química Nova |
Tipo de Acesso: | Open Access |
URI: | http://dx.doi.org/10.1590/S0100-40422011001000012 http://www.locus.ufv.br/handle/123456789/17583 |
Data do documento: | 9-Ago-2011 |
Aparece nas coleções: | Artigos |
Arquivos associados a este item:
Arquivo | Descrição | Tamanho | Formato | |
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artigo.pdf | texto completo | 438,46 kB | Adobe PDF | Visualizar/Abrir |
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