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https://locus.ufv.br//handle/123456789/18632
Tipo: | Artigo |
Título: | Aedes aegypti midgut remodeling during metamorphosis |
Autor(es): | Fernande, Kenner Morais Neves, Clóvis Andrade Serrão, José Eduardo Martins, Gustavo Ferreira |
Abstract: | The Aedes aegypti midgut is restructured during metamorphosis; its epithelium is renewed by replacing the digestive and endocrine cells through stem or regenerative cell differentiation. Shortly after pupation (white pupae) begins, the larval digestive cells are histolized and show signs of degeneration, such as autophagic vacuoles and disintegrating microvilli. Simultaneously, differentiating cells derived from larval stem cells form an electron-dense layer that is visible 24 h after pupation begins. Forty-eight hours after pupation onset, the differentiating cells yield an electron-lucent cytoplasm rich in microvilli and organelles. Dividing stem cells were observed in the fourth instar larvae and during the first 24 h of pupation, which suggests that stem cells proliferate at the end of the larval period and during pupation. This study discusses various aspects of the changes during midgut remodeling for pupating A. aegypti. |
Palavras-chave: | Midgut Development Aedes aegypti Endocrine cells Stem cells Regenerative cells |
Editor: | Parasitology International |
Tipo de Acesso: | Elsevier Ireland Ltd. All rights reserved. |
URI: | https://doi.org/10.1016/j.parint.2014.01.004 http://www.locus.ufv.br/handle/123456789/18632 |
Data do documento: | 26-Jan-2014 |
Aparece nas coleções: | Artigos |
Arquivos associados a este item:
Arquivo | Descrição | Tamanho | Formato | |
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artigo.pdf Until 2100-05-28 | Texto completo | 1,65 MB | Adobe PDF | Visualizar/Abrir ACESSO RESTRITO |
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