Use este identificador para citar ou linkar para este item:
https://locus.ufv.br//handle/123456789/13866
Tipo: | Artigo |
Título: | The ribosomal protein L10/QM-like protein is a component of the NIK-mediated antiviral signaling |
Autor(es): | Rocha, Carolina S. Santos, Anésia A. Machado, João Paulo B. Fontes, Elizabeth P.B. |
Abstract: | The NIK (NSP-interacting kinase)-mediated antiviral signaling pathway was identified as a virulence target of the begomovirus nuclear shuttle protein (NSP). Here, we further characterized this layer of plant innate defense by identifying the ribosomal protein L10 (rpL10), a QM-like protein, as a downstream effector of the antiviral signaling. Although both ribosomal proteins rpL10 and rpL18 were found to associate with NIK1 through yeast two-hybrid screening, the NIK receptors specifically phosphorylated rpL10 in vitro. Furthermore, loss of rpL10 function significantly increased susceptibility to begomovirus infection, recapitulating the phenotype of nik knockout lines. Our results genetically linked rpL10 to the NIK-mediated antiviral signaling. |
Palavras-chave: | Begomovirus Antiviral signaling NIK receptor Ribosomal protein L10 Receptor-like kinase |
Editor: | Virology |
Tipo de Acesso: | Open Access |
URI: | https://doi.org/10.1016/j.virol.2008.08.005 http://www.locus.ufv.br/handle/123456789/13866 |
Data do documento: | 2-Ago-2008 |
Aparece nas coleções: | Artigos |
Arquivos associados a este item:
Arquivo | Descrição | Tamanho | Formato | |
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1-s2.0-S0042682208005175-main.pdf | Texto completo | 424,03 kB | Adobe PDF | Visualizar/Abrir |
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